Toll-likereceptors相关论文
由于易感个体种类和耐药性病原体的增加,肺炎仍是威胁人类健康的全球问题。Toll样受体(TLR)可以在固有免疫中识别病原微生物表面的......
Background: Hepatitis C virus (HCV) infection is a worldwide issue. However, the current treatment for hepatitis C has m......
Protective Effects and Mechanisms of Shenhua Tablet (肾华片)on Toll-Like Receptors in Rat Model of Rena
Objective:To investigate the protective effects and potential mechanisms of Shenhua Tablet(肾华片,SHT) on the toll-like ......
...
Vaccination inhibits toll-like receptor transcription via suppression of glucocorticoid receptor nuc
Toll-like receptors (TLRs) and the glucocorticoid receptor (GR) act as effectors of innate immune and stress responses.T......
...
Fermented Yupingfeng Polysaccharides Enhance Immunity by Improving the Foregut Microflora and Intest
Yupingfeng (YPF) is a kind of Astragali Radix-based ancient Chinese herbal supplemented with Atractylodis Macrocephalae ......
[Background] Low back pain (LBP) is a common and remitting problem. One of the main cause of LBP is thought to be degene......
Leptospiral lipopolysaccharide induces cytokine production is toll-like receptor 2 dependent on bovi
Background: Bovine leptospirosis is a widespread infectious bacterial disease, causing serious economic losses and poten......
Asthma is a major epidemic affecting up to one third people in developed countries over the last decades, and making a c......
Hippocampal dentate granule neurons are sustainably generated from adult neural stem cells (NSCs) in the mammalian brain......
Malaria is still one of the most devastating diseases all over the world,with 40%population at risk and about 300 ~ 500 ......
The protein-protein and protein-nucleic acid interfaces have been regarded as“undruggable” despite their importance in......
Effect of antimicrobial agents on the toll-like receptors and inflammatory cytokines in liver tissue
...
目的探究外周血可溶性糖基化终末产物受体(sRAGE)、内毒素、Toll样受体(TLR)在重症急性胰腺炎(SAP)合并腹腔感染患者中的变化,并明确其与......
Anti-tumor and Phenotypic Regulation Effect of Matrine on Dendritic Cells through Regulating TLRs Pa
Objective:To investigate the effects of matrine on antigen presentation of dendritic cells (DCs),and to explore the phar......
Protein-protein and protein-nucleic acid interfaces have been regarded as "undruggable" despite their importance in ......
Toll-like receptors(TLRs)are a class of important pattern recognition molecules,which play an important role in natu......
目的 探讨慢性囊型包虫病(CE)患者外周血单个核细胞(PBMC)Toll样受体(TLRs)2、4、7基因表达变化及血清IL-10的表达情况.方法 采用实时荧......
Toll样受体(Toll—like receptors,TLRs)家族识别病原体相关分子模式(PAMPs)从而启动固有免疫应答,属于模式识别受体(PRRs)。目前关于TLRs......
Toll-like receptors (TLRs) are a central component of innate immune system and play a major role as the initiator of the......
Toll样受体(TLRs)是机体固有免疫系统的受体之一,外界微生物可与TLRs结合并激活固有免疫、炎性反应,并进一步启动获得性免疫反应.......
结核分枝杆菌是结核病的致病菌,机体免疫反应在结核菌的防御和致病中发挥关键调控作用。模式识别受体家族中的Toll样受体( TLRs)能感......
Toll样受体( TLRs)家族由13个成员组成,TLRs识别脂酸、核酸、蛋白质等配体,诱导机体产生免疫应答。而搭载配体的TLRs能够将信号传递到......
动脉粥样硬化是心脑血管疾病发生的共同病理基础,动脉粥样硬化的形成与炎症反应关系密切。最近研究表明,天然免疫应答和获得性免疫应......
Toll样受体(TLRs)可以识别外源性病原微生物的病原相关分子模式,激活下游信号通路,参与固有免疫和适应性免疫应答,也可以识别各种......
真菌性角膜炎(FK)是一种严重的致盲眼病,而Toll样受体(TLRs)在哺乳动物识别真菌的过程中发挥重要作用.大量证据表明,TLRs启动FK的......
阿托伐他汀具有强效降脂功能,目前已被广泛用于高脂血症和心血管疾病的治疗.此外,阿托伐他汀还能明显抑制白细胞介素1β(IL-1β)、......
Toll样受体是一类表达于细胞膜上的受体家族,在先天性免疫和获得性免疫系统中,起到识别微生物的作用。 Toll样受体4是最早发现的Toll......
目的 长期全胃肠外营养可导致肝脏相关并发症的发生,而Toll样受体是固有性免疫的重要组成部分,通过特异性识别病原相关分子模式,在......
Toll样受体作为一种连接先天性免疫和特异性免疫的桥梁,既在炎症反应、细胞信号转导、细胞凋亡中起重要作用,也是在肿瘤的发生发展......
目的研究慢性荨麻疹患者外周血Toll样受体(TLR)信号分子的变化及临床意义。方法选择2014年6月至2018年3月期间在本院诊断为自身免......
目的 研究外源性 α-突触核蛋白(α-syn)及其A53T突变型对星形胶质细胞的激活作用.方法 分离培养小鼠原代星形胶质细胞,经 α-syn......
目的 探讨Toll样受体(TLR)7、9在急性胰腺炎(AP)发病机制中的作用.方法 用含1、10、100 mg/L脂多糖的培养基处理正常大鼠胰腺腺泡......
Role of nitric oxide in Toil-like receptor 2 and 4 mRNA expression in liver of acute hemorrhagic nec
AIM: To investigate the role of nitric oxide (NO) in Tolllike receptor 2 (TLR2)/4mRNA expression in livers of acute hemo......
目的研究细胞因子谱及Toll样受体(TLRs)在儿童细菌感染中的表达以及临床意义。方法随机选取2014年12月至2016年6月患有全身炎症反应......
Signaling mechanisms in alcoholic liver injury: Role of transcription factors,kinases and heat shock
Alcoholic liver injury comprises of interactions of various intracellular signaling events in the liver. Innate immune r......
...
Zhuifeng tougu capsules(追风透骨胶囊)improve rheumatoid arthri-tis symptoms in rats by regulating the toll
OBJECTIVE:To investigate the efficacy of Zhuifeng tougu capsules(追风透骨胶囊,ZFTG)in the treat-ment of rheumatoid arthr......
Expression of Toil-like Receptor 2/4 on Alveolar Macrophage in the Model of Total Hepatic Ischemia/R
Objective: To explore the expression and meaning of Toll-like receptor 2/4 in alveolar macrophage during the process of ......
Toll样受体(Toll-like receptor,TLR)是新近发现的先天性免疫重要的跨膜受体和信号传导受体,通过免疫细胞表面的TLR,机体能够识别......
目的 探讨Toll样受体(TLRs)信号途径异常活化在过敏性紫癜(HSP)免疫发病机制中的可能作用.方法 采用反转录-聚合酶链反应(RT-PCR)......